Dosing and Application for the Endau Herbal Harmonizing Cream

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In general, it takes about 2 to 4 months for the progesterone in the body fat to reach physiological equilibrium for those who are menopausal, and about 1 to 2 months for those who are pre-menopausal.

Dosing and Application for the Endau Herbal Harmonizing Cream

Progesterone is best absorbed where the skin is relatively thin and well supplied with capillary blood flow.  Areas such as face, neck, upper chest, bottom of feet, top of hands and inner arms are good areas.  Spread out to as big an area as possible for maximum absorption and allow as much time for absorption as possible.  Therefore, bedtime application is best if you are applying it once a day. Twice a day application is best but it may be too troublesome for most.  Rotate to different areas to avoid saturation in any one particular site.

Practically speaking, the best gauge for the ideal dose should not be determined by any laboratory test alone. It is important to rely on relief of symptoms when figuring out the ideal dose.  The right dose is the dose that works.

The following are general recommendations for topical progesterone cream application that may need to be modified for specific situation:

Women in premenopause - still ovulating:

Use: Progesterone cream can be used to relieve PMS, painful cramps with periods, menstrual irregularities, prevent cancer and to protect against osteoporosis later in life.

?         1/2 tsp. 2Xs a day, every day for two months straight (no break)

?         3rd month, stop cream day period starts - stay off cream for 7 consecutive days.

?         Continue with this type of dosing ? 21 days on 7 days off each month. Smaller size woman would only use 1/4 tsp. 2Xs a day (same as above)

Women in peri-menopause (still menstruating with menopausal symptoms and/or PMS but not ovulating):

?         Use: Progesterone cream can be used to relieve PMS symptoms and prevent osteoporosis.

?         Directions: Count the day the period begins as the first day. 1/2 ts. twice daily from day 7 to day 27. If your period begins early, stop using Progesterone cream while you are bleeding.

Women in menopause (not menstruating):

Use: For prevention or reversal of osteoporosis and relief of menopausal symptoms.

?         1/2 Tsp. 2Xs a day, every day for one month straight (no break)

?         2nd month, stop cream for 4 consecutive days - continue with this type of dosing (27 days on, 4 days off) each month

?         Smaller size woman would only use 1/4 Tsp. 2Xs a day (same as above)

Directions for those taking an estrogen and synthetic progestin (such as Provera) combination: Stop the synthetic progestin immediately when progesterone cream is added. Estrogen should be tapped off slowly.

Dosing Progesterone Cream PMS, Younger Women & Teens

?         1/2 Tsp. 2Xs (average size body type)

?         Start dosing on day 12 (day1 being the day the period starts) then stop cream on day 26 - period should start on day 28

?         Smaller Size Woman Would Only Use 1/4 Tsp. 2Xs a day (same as above)

Infertility

You may need to suppress your ovulation for the first two months to help stimulate egg production. You do this by using the progesterone cream every day, twice a day, right through your period for two months straight. . If you are average size or heavier use ? tsp. 2xs a day. If you are on the thin side use ? tsp. 2Xs a day.

The third month purchase an ovulation monitor. The day after you ovulate start dosing as mentioned above.  If you do not get a period after starting the cream, DO NOT stop the cream, continue using it up to the 3 rd tri-mister of the pregnancy. By the third trimester the placenta will be producing 300-350 mgs per day of progesterone. If you do not get pregnant, the day you start your period stop the cream, then start it back up again the day after you ovulate and continue dosing like this until you get pregnant.

Men 42 Or Older
? tsp. once a day without taking a break. Apply to inner arms, behind the knee or on the neck.

Tapering Off the Patch:

At Powersurge, there is a transcript of an interview with Dr. Lee:
 http://www.power-surge.com/transcripts/johnlee.htm

He said "The right dose of estrogen will be found to be about 1/10 of a patch." So you could start by having cutting her patches down right away!

Here are the recommendations at Powersurge for weaning off the patch:
To taper off the patch, it is suggested you should cut each one in half,  tape the edges and continue using it that way for a month, changing it once or twice a week depending on your dosage, after which time you can stop. Or, the patches can also be cut into quarters and even eighths if symptoms persist. Other recommendations for weaning off the patch are to apply the patch every two weeks for awhile then every month to go off it.

Other Special Uses

?         Osteoporosis: Use as above for both pre and post menopause. Baseline bone mineral density (BMD) test should be obtained. If after 1 year, if the bone density increased, the amount can be reduced by half. If BMD does not increase, other factors such as exercise, diet and optimization of nutrition should be undertaken together with a full medical workup to identify other underlying causes.

?         Uterine cramps: apply above the pubic area at onset of cramps.

?         Hormone related headaches: apply creams to the sides of the neck just behind the earlobe at onset of headache. In addition to daily dosing, apply chocolate chip size doses on fingertips and massage into the sides of the head (temple area), every 20 minutes for up to 4 hours....hormonal headaches will subside or go away altogether.

?         During hot flashes: apply a small dab to the inside of the wrist at the onset of hot flashes.

?         Polycystic ovary disease: Use as stated above for you own specific circumstances~ Adjust accordingly if for longer or shorter cycle. As the hormonal balance is regained, facial hair and acne, two commonly associated symptoms, will disappear.

?         Progesterone cream and pregnancy: According to Dr. Lee, one of the chief causes of early pregnancy loss is the failure of the body to increase progesterone production sufficiently during the first several weeks after fertilization. Women who are having difficulty conceiving or who may be at risk of a miscarriage may wish to discuss with their physician to begin natural progesterone supplementation after ovulation. Also...see above for infertility support.

?         Breast cancer prevention: Breast cancer occurs most often during estrogen dominance. Dr. Graham Colditz of Harvard postulated that unopposed estrogen is responsible for 30% of breast cancer. Preventive low-dose progesterone supplementation (12-15 mg per day) can be used 24 to 25 days a month should be considered, especially for those at risk.

?         Breast cancer patient: Progesterone supplementation should be maintained for life with all breast cancer patients, before, during and after surgery.

?         Uterine fibroids: Use as stated above for your own specific circumnstances. Ultrasound tests can be obtained initially as baseline and after 3 to 6 months of use. A 10-15% reduction in size is generally expected or at least the size should not increase further. Continue this treatment until menopause if it is successful. At menopause, progesterone application can be reduced. Fibroids normally atrophy after menopause as estrogen level reduces.

?         Breast Fibrocysts: Use as above.... Also take 400 IU of vitamin E at bedtime, 600 mg of magnesium and 50 mg of vitamin B6 a day. Do also refrain from coffee and reduce sugar and fat intake. 

?         Increase Libido: Progesterone and testosterone are both important factors in libido. Testosterone is much more potent. Natural progesterone is the preferred choice.

?         Hair Loss: When progesterone level drops due to ovarian follicle failure (lack of ovulation), the body responds by increasing the synthesis of androstenedione, an adrenal cortical steroid. This has some androgenic properties, resulting in male pattern hair loss. Natural progesterone supplementation for 6 months may be helpful to reduce the androstenedione level, at which time normal hair growth will resume.

?         Hypothyroid: Thyroid hormones and estrogen have opposing actions. Progesterone also opposes estrogen. Symptoms of hypothyroid occurring in patients with unopposed estrogen or estrogen dominance (progesterone deficiency) become less symptomatic when progesterone is replaced.